David Kestenbaum follows one person as they try to find something—a set of words, some facts, a story—to convince Trump Republicans to get themselves vaccinated.

Fewer than 40 million Americans have gotten the vaccine so far, which leaves a lot of people jealous and wondering what happens inside those little rooms.

For years one group of people has been trying to push a giant boulder to the top of a hill, like Sisyphus. But in this case, it looks like they’ve actually succeeded! David Kestenbaum spoke with four scientists who have been working on a coronavirus vaccine, one that was just shown to work.

Host Ira Glass gives an update on his health status after going into quarantine last week, and David Kestenbaum interviews a 71 year old trying to avoid the virus.